Substitution Reactions
Reading & References
- Prelude to Nucleophilic Substitution and Elimination Reactions
- A First Look at Some Organic Reaction Mechanisms
- What is a Nucleophile?
- What is an Electrophile?
- What is a Leaving Group?
- Mechanistic Models for Nucleophilic Substitution (Only SN2 for CHEM 312)
Learning Goals
- Nucleophilic displacement of an Electrophile
- Nu = NaOH, NaN3, KCN
- Unimolecular mechanism only
- Alcohol substitution of halide
- Carbocation Mechanism
- No Rearrangement
- Alkoxide Nucleophiles
- Generation from alcohols with sodium Hydride